Synthesis for Biology and Medicine

The MRes in Synthesis for Biology and Medicine at the University of Oxford is a comprehensive and interdisciplinary postgraduate programme designed to equip students with advanced knowledge and practical skills in chemical synthesis, with a particular focus on applications in biology and medicine. This innovative course integrates cutting-edge synthetic chemistry techniques with biomedical sciences, enabling students to develop a deep understanding of the design and execution of complex chemical reactions and their relevance to real-world medical challenges.

Throughout the programme, students will engage with a diverse curriculum that covers core concepts such as organic synthesis, medicinal chemistry, bioconjugation, and chemical biology. They will explore how synthetic methods can be employed to create novel pharmaceuticals, diagnostic agents, and biomaterials, contributing to advancements in healthcare and biomedical research. The programme emphasizes experiential learning, offering opportunities for participants to undertake laboratory research projects under the supervision of leading experts in the field.

In addition to practical laboratory work, students will develop essential skills in scientific communication, data analysis, and research management, preparing them for careers in academia, industry, or further postgraduate research. The programme fosters a collaborative environment, encouraging interaction with fellow students, academic staff, and industry collaborators to enhance learning and professional development.

Graduates of this programme will be well-positioned to pursue careers in pharmaceutical and biotech industries, academic research, or to continue with doctoral studies. The course benefits from Oxford’s world-class facilities, extensive research networks, and its strong emphasis on translating chemical sciences into biomedical innovations. Overall, the MRes in Synthesis for Biology and Medicine offers an exceptional opportunity to acquire specialized expertise at the intersection of chemistry and medicine, contributing to the development of new therapies and diagnostic tools that address pressing healthcare challenges.

This EPSRC-led initiative is designed to build on Oxford Chemistry’s strength in synthetic chemistry and the model of inter-disciplinary scientific training within the existing Centres for Doctoral Training in Oxford.

The programme aims to train next-generation doctoral scientists in the practice of chemical synthesis coupled with an in-depth appreciation of its application to biology and medicine.  It also aims to train graduates capable of addressing major challenges across the entire remit of organic chemistry with a focus on skills relevant to the pharmaceutical and agrochemical industries.

The programme was designed in collaboration with eleven international pharmaceutical and agrochemical companies who have offered specific expertise to enhance the CDT's training and research. To ensure free exchange of information and expertise between all academic and industrial partners the CDT will adopt an intellectual property-free model consistent with its focus on basic science. 

Students are admitted to the programme without being assigned to a specific research group and will be trained initially thorough a series of taught courses in a single cohort in all aspects of organic synthesis. You will subsequently undertake two 16-week research rotations in laboratories of your choosing before joining a specific group for a substantive three-year DPhil research project. To enable significant and long term research goals to be tackled, research projects will be clustered into six broad areas ('project fields'):

• new synthetic methods
• 3D templates for ‘lead-like’ compounds
• functional probes for epigenetics
• next-generation anti-infectives
• natural product chemistry
• tools for neuroscience

During all four years of the programme, you will also receive a tailored programme designed to broaden their research and professional skills.

For the first year, you will be housed in the purpose-built facility located in the Rex Richards Building. This will be the location of the taught courses and contains a large, open plan office designed expressly to facilitate cohort-interaction and interdisciplinary training. 

At an appropriate stage you must pass Transfer of Status. This will normally be at the end of your fifth term, but you will have up to six terms to complete this stage. This assessment will be made on the basis of a report and oral examination.

Applicants are normally expected to be predicted or have achieved a first-class or strong upper second-class undergraduate degree with honours (or equivalent international qualifications), as a minimum, in a relevant chemical sciences subject.

For applicants with a degree from the USA, the minimum GPA sought is 3.6 out of 4.0.

However, entrance is very competitive and most successful applicants have a first-class degree or the equivalent.

A previous master's degree (either an integrated master's degree or standalone) is preferred but is not required. Substantial professional experience or a graduate qualification may be a substitute for a lower grade at undergraduate level.     

If you hold non-UK qualifications and wish to check how your qualifications match these requirements, you can contact the National Recognition Information Centre for the United Kingdom (UK NARIC).

No Graduate Record Examination (GRE) or GMAT scores are sought.

• Official transcript(s)
• CV/résumé
• Statement of purpose:Up to 1,000 words
• References/letters of recommendation:Three overall, generally academic

ENGLISH LANGUAGE REQUIREMENTS

Higher level

The Synthesis for Biology and Medicine program at the University of Oxford offers various funding opportunities to support students throughout their studies. Students applying for this program can explore a range of scholarships, grants, and financial aids provided by the university, government, and external organizations. Oxford University provides a comprehensive scholarship scheme for both national and international students, tailored to diverse backgrounds and academic achievements. These include the Rhodes Scholarship, Clarendon Fund, and specific departmental bursaries that support students pursuing advanced degrees in biological sciences and medicine. Additionally, students are encouraged to apply for external funding from government agencies, research councils, and charitable foundations relevant to their field of study. The university also facilitates access to loans and payment plans for eligible students, helping to manage tuition fees and living expenses effectively. Many funding options are merit-based, considering academic excellence, research potential, and financial need. Moreover, students are advised to consult the university’s dedicated financial support office for personalized guidance and to ensure they are aware of all available resources. The program’s duration typically spans one to two years, depending on the specific course structure and research commitments, and students are encouraged to seek funding at the earliest opportunity. International students should also explore specific scholarships aimed at supporting overseas students, which may include top-up awards and mobility grants. The university’s aim is to make postgraduate study accessible by providing a broad spectrum of financial aid that covers tuition fees, stipends, research costs, and other necessary expenses. Overall, the financing options for Synthesis for Biology and Medicine are designed to enable talented students to pursue their academic and research ambitions without financial barriers, fostering an inclusive and vibrant academic community at Oxford.

Synthesis for Biology and Medicine is a specialized interdisciplinary program offered at the University of Oxford, designed to equip students with a comprehensive understanding of the molecular and cellular mechanisms underlying biological processes and medical sciences. The program integrates principles from chemistry, biology, and medicine, facilitating the development of skills necessary for innovative research and practical applications in healthcare, pharmaceuticals, and biotechnology sectors. Students enrolled in this program have opportunities to engage in cutting-edge research projects, often working in collaboration with leading academics and medical professionals across the university facilities and associated hospitals. The curriculum emphasizes both theoretical knowledge and hands-on laboratory experience, fostering critical thinking and problem-solving abilities. Throughout the course, students explore diverse topics such as biochemistry, molecular biology, pharmacology, and medical genetics, which are vital for understanding disease mechanisms and developing targeted therapies. The program is structured to prepare graduates for careers in biomedical research, clinical medicine, healthcare policy, or further postgraduate studies. Graduates benefit from Oxford’s extensive network of research institutes, hospitals, and industry partnerships, providing avenues for internships, research attachments, and professional development. Teaching is delivered by world-renowned faculty, with a curriculum that is continually updated to reflect advances in science and medicine. Students also develop essential transferable skills, including scientific communication, data analysis, and ethical considerations in biomedical research. Overall, the program aims to produce well-rounded scientists capable of contributing meaningfully to the advancement of medical science and improving patient care through innovative research and application.