Chromosome and Developmental Biology

Chromosome and Developmental Biology at the University of Oxford offers students a comprehensive and in-depth exploration of the fundamental mechanisms that underpin human development and genetic inheritance. This programme is designed for students with a strong interest in genetics, cell biology, molecular biology, and developmental processes, providing an excellent foundation for careers in biomedical research, biotechnology, healthcare, and academic pursuits. Throughout the course, students will study the structure and function of chromosomes, mechanisms of gene expression, regulation of developmental pathways, and the genetic basis of developmental disorders. The curriculum combines theoretical knowledge with practical laboratory skills, enabling students to perform genetic analyses, microscopy, and molecular biology techniques. In addition to core biological sciences, the programme emphasizes critical thinking, research methodology, and data analysis, preparing students for independent scientific investigation. The programme is delivered by world-renowned researchers and experts in the field, ensuring students receive cutting-edge education aligned with current scientific advances. Students will also have the opportunity to engage in research projects, internships, and collaborative work, fostering a deeper understanding of developmental genetics and its applications in medicine and biotechnology. The programme aims to equip graduates with the knowledge and skills necessary to contribute to scientific discoveries relevant to human health, developmental processes, and genetic engineering. Extensive support services, small class sizes, and access to state-of-the-art facilities ensure an engaging and supportive learning environment. Graduates of the programme are well-prepared for further study at the postgraduate level, including MSc and PhD programmes, or for entry into research, clinical, and industry roles within the biomedical sector. Overall, the Chromosome and Developmental Biology programme offers a rigorous, research-led education that combines biological theory, laboratory practice, and critical analysis, shaping the next generation of scientists and innovators in genetics and development.

Participating laboratories are international leaders in the fields of chromosome regulation through the mitotic and meiotic cell cycle, the regulation of genome stability and mechanisms of DNA repair, gene/genome regulation in development, including mechanism of transcription, the role of chromatin, nuclear organisation and epigenetic pathways, RNA biogenesis and function (including non-coding RNA), regulating cell fate and pattern formation (including signalling mechanisms and stem cell biology).

Applicants are advised to visit the Medical Sciences Graduate School website for further information about supervisors connected to this programme.

The programme provides training in a wide range of biochemical, genetic and cell biological approaches specifically tailored for research into chromosome and developmental biology. A clear priority is to provide students with training and supporting infrastructure to apply advanced biological imaging/super resolution microscopy, high-throughput sequencing method (and computational genomics for data analysis), advanced proteomics and state-of-the-art genome engineering.  

During the first two months of the first year you will attend integrated advanced courses, workshops and tutorials linked to applying state of the art methodologies in chromosome and development research. Further short tutorial sessions will occur at other times during the year.

You will then undertake three 12-week projects, each in a different lab. At least one of these will involve the application of state-of-the-art methodologies detailed above. There will be opportunities to present your results both orally and in written reports.

These elements are intended to expose you to possible thesis advisers and prepare you for your doctoral work. You can then make an informed choice of your main thesis research project and submit a research proposal for years two to four.

You will be required to meet standard University milestones for progress and will be monitored formally via supervisor feedback forms submitted three times per year.

Applicants are normally expected to be predicted or have achieved a first-class or strong upper second-class undergraduate degree with honours (or equivalent international qualifications), as a minimum, in a relevant biological sciences subject.

For applicants with a degree from the USA, the minimum GPA sought is 3.5 out of 4.0. However, entrance is very competitive and most successful applicants have a first-class degree or the equivalent.

If you hold non-UK qualifications and wish to check how your qualifications match these requirements, you can contact the National Recognition Information Centre for the United Kingdom (UK NARIC).

Substantial professional experience or a graduate qualification may be a substitute for a lower grade at undergraduate level.

No Graduate Record Examination (GRE) or GMAT scores are sought.

• Official transcript(s)
• CV/résumé
• Statement of purpose/personal statement: Up to three pages
  References/letters of recommendation: Three overall, all of which must be academic

ENGLISH LANGUAGE REQUIREMENTS

Standard level

Funding for the Genetics, Development and Disease MSc program at the University of Oxford is available through various sources to support students financially throughout their studies. The university offers a range of scholarships, bursaries, and grants specifically targeted at postgraduate students. These include the Clarendon Fund, which provides substantial funding opportunities for excellent applicants regardless of nationality, and the Oxford Graduate Scholarships, which support students in need of financial assistance. Many departmental scholarships are also available, awarded based on academic merit or financial need, and some are specific to students pursuing studies in Genetics, Developmental Biology, or related fields. In addition, some students may be eligible for external funding from government agencies, research councils, or professional bodies in their home country. Teaching assistantships and research assistant positions within the Department of Physiology, Anatomy and Genetics provide additional financial support, often involving a stipend and tuition fee remission. The university also encourages students to explore part-time work opportunities and external scholarship programs that may assist with living expenses and tuition fees. Prospective students are advised to thoroughly review the university's official funding pages and contact the department directly for tailored advice regarding financial planning and available funding packages. As funding options can vary annually and depend on individual circumstances, students are encouraged to apply early and ensure they meet all application requirements for scholarships and grants. Overall, students enrolled in the program have access to a comprehensive support network to help alleviate financial burdens and focus on their academic and research goals during their time at Oxford.

The Bachelor's degree in Chromosome and Developmental Biology at the University of Oxford offers students a comprehensive understanding of the fundamental processes that govern genetic inheritance and organism development. This program is designed to equip students with an in-depth knowledge of molecular genetics, cell biology, developmental biology, and chromosome structure and function. Throughout the course, students explore how chromosomes influence development, how genetic information is transmitted, and the mechanisms underlying genetic variation and chromosomal abnormalities. The curriculum combines theoretical lectures with practical laboratory sessions, allowing students to gain hands-on experience in modern genetic techniques, microscopy, and data analysis. Students will also examine the implications of genetic research in medicine, agriculture, and biodiversity conservation. The program emphasizes critical thinking, problem-solving, and research skills, preparing graduates for careers in biomedical research, clinical genetics, biotechnology, and related fields. Additionally, students may have access to cutting-edge research facilities and participate in projects that contribute to current scientific advancements. The program fosters an interdisciplinary approach, integrating knowledge from biology, chemistry, and computer science to address complex biological questions. Graduates of this program will be well-equipped to pursue postgraduate studies or careers involving genetic research, developmental studies, and chromosome analysis. Overall, the Cell and Developmental Biology program at Oxford aims to produce highly skilled scientists capable of advancing our understanding of life's fundamental processes and translating discoveries into practical applications that benefit society.