Molecular Cell Biology

The Molecular Cell Biology graduate program at Washington University in St. Louis offers a comprehensive and rigorous education designed to prepare students for a successful career in biomedical research, academia, industry, or healthcare. This program provides an in-depth understanding of the fundamental molecular mechanisms that govern cellular processes, including gene expression, signal transduction, cell cycle regulation, and membrane dynamics. Students have access to state-of-the-art laboratories and collaborate with renowned faculty members who are leaders in their respective fields. The curriculum integrates coursework, laboratory research, and seminars, fostering a broad and deep understanding of molecular and cellular biology concepts. Graduates develop critical thinking, experimental skills, and a solid foundation in scientific methodology, positioning them for competitive careers in research institutions, biotech companies, pharmaceutical industries, and further academic pursuits such as PhD or MD programs. The program emphasizes interdisciplinary approaches, combining molecular biology, genetics, biochemistry, and biophysics to address complex biological questions. Students may participate in cutting-edge research projects that contribute to the understanding of health and disease, including cancer, neurodegenerative disorders, infectious diseases, and genetic conditions. The mentoring by faculty mentors ensures personalized guidance and support throughout the student’s academic journey. Graduates leave equipped not only with technical expertise but also with the ethical and professional standards necessary for impactful scientific advancement. The program is committed to fostering a diverse and inclusive academic community, encouraging innovative ideas, and promoting collaborative research efforts. Whether pursuing a research-intensive career or applying their knowledge in translational medicine, students graduate from this program prepared to make significant contributions to the field of molecular and cellular biology.

Typically a graduate student begins the Program in late August and enrolls in two core courses:

• Fundamentals of Molecular Cell Biology (Bio 5068)
• Nucleic Acids and Protein Biosynthesis (Bio 548) 

Students will be required to take one advanced elective from the list below. Because of the diversity of interest within the Program, departments and laboratories sharing common interest have organized a number of more focused, advanced courses which are offered to second-, third-, and fourth-semester students. These include:

• Advanced Genetics (Bio 5491)
• Biology and Pathology of the Visual System (5501)
• Biotech Industry Innovators (Same as B63 MGT 500U) (Bio 5014)
• Computational Molecular Biology (Bio 5495)
• Developmental Biology (Bio 5352)
• Immunobiology I (Bio 5053)
• Immunobiology II (Bio 5054)
• Macromolecular Interactions (Bio 5312)
• Molecular, Cell and Organ Systems (Bio 5224)
• Molecular Microbiology and Pathogenesis (Bio 5392)

In addition, students will take 2 units of the journal clubs listed below and are organized by several laboratories with overlapping interest.

• Advanced MRI Techniques (same as Home E72 BME 505) (Bio 5465)
• Cancer Biology (Bio 5192)
• Cardiovascular Biophysics (same as Home E62 BME 5911) (Bio 5468)
• Clocksclub (Bio 5678)
• Computational Molecular Biology (Bio 5496)
• Current Research in Chromatin, Epigenetics and Nuclear Organization (Bio 5284)
• Current Topics in Biochemistry (Bio 5466)
• Development, Regeneration & Stem Cell Biology (Bio 5152)
• DNA Metabolism (Bio 5445)
• Experimental Hematopoiesis (Bio 5123)
• Experimental Skeletal Biology (Bio 5255)
• Extracellular Matrix and Cell Matrix Interactions (Bio 5128) 
• Genetics (Bio 5235) 
• Genetics and Development of C. elegans (Bio 5484)
• Hematology/Oncology (Bio 5417)
• Ion Channels (Bio 5137)
• Imaging Science & Engineering (same as Home E35 ESE 596) (Bio 5139)
• Metabolism (Bio 5148)
• Misfolding & Aggregation (Bio 5334)
• Molecular Mechanism of Aging (Bio 5138)
• Molecular Microbiology and Pathogenesis (Bio 5416) 
• Molecular Virology (Bio 5393)
• Nanomedicine Applications (Bio 5145)
• Oral Presentation of Scientific Data (Bio 5565)
• Plant and Microbial Biology (Bio 5720)
• Protein NMR (Bio 5303)
• RNA Biology (Bio 5151)
• Synapses (Bio 5577)
• Structural Biology (Bio 5328)
• Tropical and Molecular Parasitology (Bio 5412)

Students will also complete a course in Ethics (Bio 5011) during the Spring of their second year.

Along with courses, the program emphasizes laboratory experience. First-year students typically rotate through three laboratories and most have establishes themselves in a thesis laboratory by the spring of the first year.

Requirements

• Demographics
• Three letters of recommendation
• Academic history
• Test Scores 
  •  GRE
  • TOEFL (if applicable)
• Two essays and a 10 word research description
• Listing of Major coursework
• Work history
• Awards/Honors
• Publication list (if any)
• Payment of $45 application fee by credit card as part of the on-line application or obtain a fee waiver (please see fee waivers FAQ for additional information).

Scholarships

• Chancellor's Graduate Fellowship Program
• Need-based financial aid assistance
• Merit-based scholarships
• McDonnell International Scholars Academy

The Molecular Cell Biology program at Washington University in St. Louis offers an in-depth exploration of the fundamental aspects of cellular and molecular processes that underlie biological functions and disease mechanisms. This graduate program is designed for students aiming to develop a comprehensive understanding of cell structure, function, signaling, genetics, and biochemistry, preparing them for careers in research, academia, biotechnology, and healthcare. Students engage in a rigorous curriculum that includes coursework in molecular biology techniques, genetics, biochemistry, and cell biology, complemented by extensive laboratory research. The program emphasizes both theoretical knowledge and practical skills, fostering a hands-on approach to scientific inquiry.

Graduate students have access to state-of-the-art research facilities and collaborate with leading faculty members who are at the forefront of research in cell and molecular biology. The program encourages interdisciplinary approaches, integrating aspects of biochemistry, genetics, immunology, and structural biology to solve complex biological questions. Students typically participate in seminars, research presentations, and journal clubs, enhancing their scientific communication and critical thinking abilities.

The faculty involved in the Molecular Cell Biology program are renowned for their contributions to understanding cell signaling, gene regulation, developmental biology, and the molecular basis of diseases like cancer and neurodegeneration. Many students in the program also have opportunities for teaching assistantships, research assistantships, and external funding, which support their academic progress and professional development. The program culminates in the completion of a thesis based on original research, leading to a Master’s or Ph.D. degree depending on the student's chosen pathway.

Graduates of the program are well-equipped to pursue careers in academic research, biotechnology, pharmaceutical industries, and science policy, or to continue their education through postdoctoral fellowships. Washington University in St. Louis is committed to fostering an inclusive and dynamic academic environment that promotes innovation, collaboration, and excellence in scientific research. Overall, the Molecular Cell Biology program prepares students to contribute significantly to advancements in understanding cellular processes and developing novel therapeutic strategies.