Neurobiology

The Neurobiology program at the California Institute of Technology offers students a comprehensive and rigorous education in the fundamental principles underlying the nervous system and its functions. This interdisciplinary program integrates biology, chemistry, physics, mathematics, and engineering to provide a holistic understanding of neural mechanisms, from molecular and cellular processes to systems-level functions and behaviors. Students will engage in cutting-edge research, experimental techniques, and theoretical approaches to explore topics such as neural development, neurophysiology, learning and memory, sensory and motor systems, and neuroinformatics. The program emphasizes hands-on laboratory experience and encourages innovative problem-solving, preparing graduates for careers in academia, industry, healthcare, and public policy. With access to state-of-the-art facilities and close collaboration with leading faculty members, students will have ample opportunity to contribute to significant discoveries in neuroscience. The curriculum is designed to foster critical thinking, computational skills, and interdisciplinary collaboration, ensuring that graduates are equipped to address complex scientific questions and contribute meaningfully to advances in understanding the brain and nervous system. Through seminars, workshops, and participation in ongoing research projects, students will stay abreast of the latest developments in neurobiology. Graduates of the program will be well-positioned to pursue doctoral studies in neuroscience, psychology, medicine, or related fields, or to enter research and development roles in biotechnology, pharmaceuticals, and healthcare industries. The Neurobiology program at Caltech is committed to fostering innovative scientific inquiry and training the next generation of neuroscientists to unravel the complexities of the nervous system and improve human health.

First-year advisor

Each incoming student is paired with an academic advisor during the first year. This mentor will guide the student in course selections and other decisions, taking the student’s background into account. Where possible, this advisor will not be one of the prospective rotation supervisors.

Rotations

First-year students carry out three laboratory rotations, each lasting one quarter. At least two of these should be with faculty participating in the option. By June 30 of the first year students choose a PhD advisor.

Formal Classes

Students take at least 6 quarter courses (54 units) as follows:

• One course in molecular, cellular, developmental neurobiology;
• One course in circuits, systems, behavioral biology;
• One course in mathematical methods (depending on student background);
• BE/CNS/NB 164, Tools of Neurobiology;
• Two electives.
   

In addition students take a short course on responsible conduct of research (Bi 252). All courses must be taken for a grade unless only offered pass/fail.

Teaching

Students serve as teaching assistants for three terms.

Admission to Candidacy

To qualify for candidacy the student must first demonstrate broad competence by passing each of the first-year courses with a grade of B or higher. Failure here can be remedied by successful second year coursework. By June of the second year, the student must also defend a thesis proposal in an oral exam before a qualifying exam committee of at least 3 faculty. This exam will also cover general knowledge in the relevant field. With special permission the oral exam may be retaken once before the end of winter quarter of the third year. Students that do not advance to candidacy by the end of the third year may not continue in the program.

Thesis Advisory Committee

Once admitted to candidacy, the student chooses a thesis advisory committee of at least 3 faculty. This committee serves as a source of advice independent of the PhD supervisor throughout the student’s tenure. Each year, before the end of June, the student delivers a written progress report, followed by a meeting with the thesis advisory committee.

Thesis Examination Committee

This committee is usually the same as the thesis advisory committee, but this need not be the case. The final oral examination covers principally the work of the thesis, and according to Institute regulations must be held at least two weeks before the degree is conferred.

Requirements

• Applicants are expected to have studied college-level mathematics, physics, chemistry, and biology. They should also have experience in independent research. Coursework in neurobiology and experience in scientific computing are helpful but not required. Whenever possible, applicants will be invited to campus before final admission decisions are made.
• Statement of Purpose
• Include payment of the application fee or submit a fee waiver request. 
• Three letters of recommendation from individuals familiar with your academic and/or work performance are required for all applicants. 
• Transcripts from all colleges or universities attended are required. Transcripts may be sent directly from the Registrar of the institution you attended or transcripts issued directly to the applicant, and so marked, are acceptable, and can be submitted online following the electronic submission process. If you attended Caltech as an undergraduate, you must request an official transcript from the Office of the Registrar. We cannot obtain one on your behalf. 
• Attach a CV or resume
• TOEFL

The Neurobiology program at the California Institute of Technology (Caltech) offers a comprehensive curriculum supported by various financial aid options to ensure accessible education for talented students. Caltech is committed to providing financial assistance through a combination of scholarships, grants, and work-study opportunities. Undergraduate students in the Neurobiology program are encouraged to explore the Caltech Financial Aid Office’s resources, which include need-based aid that covers a significant portion of tuition and associated costs. Graduate students may have access to fellowships, research grants, teaching assistantships, and other funding sources designed to support their research activities and academic pursuits. Caltech's financial aid policies emphasize meeting 100% of demonstrated financial need for all admitted students, utilizing a need-blind admissions process for undergraduates. Additionally, the institution offers merit-based awards and stipends for students engaged in research projects within the Neurobiology program. International students are also eligible for various scholarships and financial aid programs, making the program accessible to a diverse student body. The university’s extensive alumni and donor network provides ongoing support for funding initiatives, ensuring that financial constraints do not impede students’ educational and research ambitions. Prospective and current students are advised to consult Caltech’s official financial aid resources for detailed information on application procedures, eligibility criteria, and deadlines related to Neurobiology studies. Overall, the Caltech Neurobiology program benefits from a robust financial framework designed to support innovative research and academic excellence, fostering an inclusive environment for students from various socioeconomic backgrounds.

The Neuroscience program at the California Institute of Technology (Caltech) offers a comprehensive interdisciplinary education focusing on the fundamental mechanisms of the nervous system. This program integrates coursework and research opportunities across biology, chemistry, physics, and engineering disciplines, reflecting Caltech’s commitment to fostering innovative approaches to understanding neural function and behavior. Students in the program are exposed to a wide array of topics including neuroanatomy, neurophysiology, molecular neuroscience, computational neuroscience, and neuroengineering, enabling them to develop a versatile skill set applicable to diverse research settings and careers.

The program emphasizes hands-on laboratory experience, allowing students to work with state-of-the-art equipment and methodologies, such as electrophysiology, imaging techniques, and theoretical modeling. This practical training prepares graduates to contribute significantly to the fields of biomedical research, pharmaceuticals, and neurotechnology. Additionally, students have opportunities to collaborate with faculty members renowned for their contributions to neuroscience and related fields, often participating in groundbreaking research projects that push the boundaries of current scientific knowledge.

Caltech’s strong culture of innovation and its proximity to numerous research institutions provide students with unique opportunities to engage in cutting-edge neuroscience research. The curriculum is designed to foster critical thinking, problem-solving, and technical skills, equipping students to address complex questions about brain function, neurological disorders, and potential therapeutic strategies. Graduates of the program are well-positioned to pursue careers in academia, industry, or continued graduate studies, with a solid foundation in both experimental and theoretical approaches to neuroscience.

The university also offers various seminars, workshops, and conferences that allow students to present their research findings, network with professionals in the neuroscience community, and stay updated with the latest developments in the field. Overall, the Caltech Neurobiology program aims to cultivate innovative scientists capable of advancing our understanding of the nervous system and developing solutions to neurological challenges facing society today.