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The aim of this postgraduate Translational Neuroscience programme, which is at present the first of its kind in the UK and Europe, is to provide a thorough training in the main concepts and methods of translational medicine, with a particular focus on unmet needs in diseases of the nervous system and the challenge of developing better therapies. At the end of their studies students will have a detailed knowledge of the drug discovery and development process, and of clinical trial design and methodology and the regulatory environment.
The formal teaching takes place in the Neuroscience Centre at the Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, and includes lectures, seminars, clinical workshops and a research project. The lecturers are specialists in their field and are pre-clinical scientists and clinicians, and are internationally renowned as leaders in their field. There are also invited speakers, who are specialists from other UK or international academic institutions and senior scientists from the pharmaceutical industry.
The programme provides coverage of the following topics:
* Basic principles in neuroscience
* Mechanisms of disease and drug targets in the nervous system
* Unmet therapeutic needs in major disease areas in neurology
* Biomarkers of disease and their role in drug development
* Genomics, proteomics, metabolomics and systems biology and their impact in modern medicine
* Drug discovery
* Drug development
* Clinical trial design and regulatory requirements
* Intellectual property
The taught programme starts with a core module which covers fundamental concepts in drug discovery and development, and continues with five special modules which cover comprehensively specific disease areas. The taught programme is delivered in two half-days per week, throughout the academic year. After the completion of the taught programme, students carry out a research project, which can be library-based, laboratory-based or clinically-based.
Assessment The taught modules are assessed using a combination of final written examinations and a series of in-course assessments. The in-course assessments consist of literature reviews, oral presentations, case analyses and clinical trial protocols. They are designed as a learning experience as well as a test of knowledge. They represent 30 per cent of the module marks. The research project assessment is based on a written dissertation and an oral examination, which represent 85 per cent and 15 per cent of the mark, respectively.