Biochemistry

The Biochemistry program at the University of Toronto offers students an in-depth exploration of the chemical processes and molecular mechanisms that underpin living organisms. Designed for those interested in understanding the intricate chemistry of life, this program combines foundational courses in chemistry and biology with specialized studies in biochemistry, molecular biology, and related disciplines. Students will gain a comprehensive understanding of cellular processes, metabolic pathways, enzyme functions, and genetic regulation through rigorous coursework and laboratory research.

The Bachelor of Science in Biochemistry provides a strong scientific foundation, preparing graduates for diverse careers in research, healthcare, biotechnology, and academia. The program emphasizes both theoretical knowledge and practical skills, enabling students to perform complex experiments, analyze scientific data, and apply their knowledge to real-world problems. Students have access to state-of-the-art laboratories and research facilities, fostering hands-on learning and innovation.

Throughout the program, students are encouraged to engage in research projects under the guidance of experienced faculty members, allowing them to contribute to cutting-edge discoveries in the field. The curriculum also includes opportunities for internships, cooperative education, and collaborations with industry partners, enhancing employability and professional development.

Graduates of the Biochemistry program at the University of Toronto are well-equipped to pursue graduate studies, professional health programs, or careers in scientific research, pharmaceuticals, diagnostics, and environmental sciences. The program’s interdisciplinary approach ensures that students develop critical thinking, problem-solving skills, and a strong ethical understanding of scientific practices. With a commitment to academic excellence, innovation, and community engagement, the University of Toronto’s Biochemistry program prepares students to become future leaders in science and technology.

Students in the Ph.D. stream must complete the equivalent of 1 & 1/2 credits in graduate course work, attend the weekly student seminar regularly, give three student seminars, and conduct regular committee meetings. During their tenure, the student will have conducted independent and original research that will form their thesis. In addition, they will have demonstrated in-depth knowledge of not only their scientific field, but that of related fields. While there is no strict requirement for their work to be published in peer-reviewed literature, it is expected that the work done is of publishable quality. Typically the Ph.D. thesis contains an introduction, methods, two or three data chapters, and conclusions. Students typically take 5-6 years to complete their Ph.D.

Most students enter the program as an M.Sc. student, although there are exceptions whereby students enter directly into the Ph.D. program. A majority of students by-pass their M.Sc. and transfer into the Ph.D. program at the 18 month point in their tenure.

• BCH2024H – FOCUSED TOPICS
• BCH1426H – REGULATION OF SIGNALLING PATHWAYS
• BCH1440H – PROTEIN BIOSYNTHESIS
• BCH1441H – BIOINFORMATICS
• JBB1425 – STRUCTURAL BIOLOGY: PRINCIPLES AND PRACTICE
• JBB 2025H – PROTEIN CRYSTALLOGRAPHY
• JBB2026H – PROTEIN STRUCTURE, FOLDING AND DESIGN
• JTB 2020H – APPLIED BIOINFORMATICS

1. Online application (submitted electronically)
2. Letter of Intent (submitted electronically) 1 – 2 pages
3. Curriculum Vitae (submitted electronically) 1 – 3 pages
4. Three letters of reference (submitted electronically)
5. Official transcripts from ALL university programs attended (submitted electronically)

 Additionally, applicants from Universities outside Canada must submit:

1. TOEFL exam (University of Toronto code: 0982)
2. GRE General Test (University of Toronto code: 0982)

Applicants educated outside of Canada require a degree equivalent to that of a Canadian Honours/Specialist degree (i.e. a four-year degree) as described above. In some cases this may be an M.Sc. degree. It should be in biochemistry, molecular biology, cell biology, or in a related subject area before being considered for entry into our graduate program.

A GRE General Test score is also required. A minimum score of 80% is required in BOTH Verbal Reasoning and Quantitative Reasoning.   GRE scores are valid for 5 years after the testing year in which you tested (July 1 – June 30).

 English Language Proficiency (TOEFL Test)

If the language of instruction at your university is not English*, we require an English language test. Minimum acceptable scores for TOEFL or an equivalent English-language facility test are as follows:

• Minimum paper-based score: Overall score 580 / TWE 5
• Minimum computer-based score: Overall score 237 / Essay rating 5
• Internet-based test and writing and speaking sections: Overall score 93 / Writing score 22 / Speaking score 22

Scholarships

All graduate students are expected to apply for external scholarship support (e.g. OGS, CIHR, NSERC etc.) when eligible. A student who receives $15,000 or more as a major, competitive, external scholarship will receive a $4,000 merit bonus, which is added to his/her stipend for the duration of the award.  Awards eligible for the merit bonus must not be restricted to a limited group of students, such as those at a hospital-based research institute.

Students performing projects in one of 32 labs investigating protein biochemistry can apply for funding to the CIHR Training Program in Protein Folding.

The University of Toronto offers a comprehensive Biochemistry program that provides students with a strong foundation in the chemical processes occurring within and related to living organisms. This program integrates principles from chemistry and biology to explore the molecular mechanisms underlying life processes. Students enrolled in the Biochemistry undergraduate degree will have opportunities to study diverse topics such as enzymology, molecular genetics, structural biology, metabolic pathways, and cellular signaling. The curriculum often includes a combination of coursework, laboratory research, and practical experience designed to develop both theoretical understanding and hands-on skills.

The program aims to prepare students for careers in scientific research, healthcare, biotechnology, or further graduate studies. The university facilities support rigorous scientific inquiry with state-of-the-art laboratories and research centers. Students may also have access to internships and collaborative projects with industry partners or research institutions. From introductory courses to advanced topics, the program emphasizes critical thinking, experimental techniques, data analysis, and scientific communication. Graduates of the Biochemistry program at the University of Toronto are well-equipped for roles in research laboratories, pharmaceutical companies, healthcare settings, or to pursue graduate studies in biomedical sciences, biochemistry, or related fields. The University of Toronto's reputation as a leading research university enhances opportunities for students to engage in innovative projects and contribute to cutting-edge scientific advancements.